Series A: A Series — April 2026
Powered by Obviously NYC, presented by Gunderson Dettmer, HubSpot for Startups, PwC US, and SVB.
April 2026’s Series A: A Series adds 21 new companies that just crossed the Series A milestone, and together they’re already hiring for 110+ NYC-based jobs.
But beyond the company count, April tells a much bigger story about where venture capital — and New York’s startup ecosystem — is heading in 2026.
The headline is that checks are getting much bigger.
This April cohort brought in a combined $606.3 million in Series A funding alone (with ~30% fewer companies) — a massive jump from the $356.4 million raised by the 30 NYC founders who closed a Series A in April 2025.
Total funding across all rounds in April reached $754.3 million, up from $645.1 million last year. The majority of funding in April 2026 went to Series A rounds.
The average Series A round nearly doubled year-over-year, climbing from $13.7 million in April 2025 to $31.9 million this year.
What’s especially notable is that the gap between “Series A capital” ($606.3 million in April 2026 vs. $356.4 million in April 2025) and “total historical funding” ($754.3 million vs. $645.1 million) narrowed significantly compared to last year. That means startups are raising larger institutional rounds earlier in their lifecycle, rather than stacking multiple smaller pre-Series A rounds beforehand.
It also suggests growing investor confidence — not just in AI broadly, but specifically in NYC startups building durable infrastructure businesses in healthcare, fintech, enterprise operations, and security.
AI Infrastructure Continues to Dominate
If there’s one defining theme from April’s cohort, it’s that NYC founders are building the operational layer for the AI economy.
Roughly half the companies in this month’s cohort are focused on AI-native enterprise infrastructure, workflow automation, or operational tooling.
But unlike the early generative AI boom — dominated by experimentation and copilots — this next wave is embedding directly into core business systems.
Companies likeAmperos,Manifest,Auctor,Zenskar,Mosaic, andDecision Science Advisors are applying AI to: healthcare administration, legal workflows, billing and revenue operations, and more.
Digital Health Infrastructure Keeps Accelerating
Digital health was one of April’s strongest verticals by both company count and funding raised.
Five companies in this month’s cohort operate directly in healthcare or health infrastructure:
Together, those companies raised a combined $106 million in Series A funding. These startups are rebuilding the operational backbone of healthcare itself, which reflects a broader trend we’ve seen across NYC’s startup ecosystem over the last year: healthcare innovation increasingly means fixing fragmented systems.
Fintech Evolves Into Financial Infrastructure
Fintech remains one of NYC’s defining strengths — but the category itself keeps evolving.
This month’s cohort included startups focused on cross-border payments, audit infrastructure, institutional finance, and more.
Companies likeOpenFX,Blockworks,Modus Alliance,Mosaic, andZenskar show how NYC fintech is shifting toward institutional-grade infrastructure and operational tooling.
In other words, more foundational systems powering how money moves behind the scenes.
Trust Infrastructure Is Becoming Its Own Category
As AI adoption accelerates, governance, security, and compliance infrastructure are rising alongside it.
Companies likeArtemis Security,Cybord, andHaast are building systems focused on AI-native protection layers, hardware supply chain integrity, automated compliance monitoring, and trust infrastructure for regulated industries.
From Series A to IPO: Bringing Founders Together at Nasdaq
Photo credit: Nasdaq
Each quarter, we gather a group of these NYC founders who raised a recent Series A round to celebrate this milestone achievement, highlight momentum in the NYC startup ecosystem, and learn from a founder who’s been through it all.
We recently gathered 20+ founders who raised a Series A in Q1 at Nasdaq for margaritas and tacos on the terrace, and a fireside chat with Datadog Co-Founder & CTO Alexis Lê-Quôc on scaling from Series A to IPO.
The conversation touched on building through market cycles, scaling technical organizations, and why NYC has become one of the strongest places in the world to build enduring technology companies.
The Bigger Picture
Taken together, April’s cohort reinforces that NYC’s startup ecosystem is maturing. The city is producing companies that are raising larger rounds earlier, hiring aggressively, and building foundational systems for major industries like healthcare, finance, enterprise software, and AI operations.
These are the next generation of category-defining companies being built in New York. And judging by April’s numbers, investors increasingly believe that too.
Did we miss your Series A raise? Let us know — we want to spotlight every NYC founder turning vision into venture.
Latest Series A funding rounds in NYC:
Last updated: May 1, 2026.
The map below features raises from June 2025 - April 2026.
The sheet below is sorted by most recent raise date.